Introduction: Schizophrenia is a severe neuropsychiatric disorder of unknown etiology. Toxoplasma has emerged as an interesting candidate as a possible cause of some cases of schizophrenia. Studies have found a high seroprevalence of T. gondii in schizophrenia patients Methods: In the present study 82 patients suffering from schizophrenia (68 were male and 14 were female) were examined for the presence of IgM antibodies against T. gondii by enzyme-linked immunosorbent assay (ELISA). Results: The positivity rate of anti- Toxoplasma gondii IgM antibodies among individuals with schizophrenia (4.5%), there were associations between T. gondii seropositivity and gender. Conclusion: Toxoplasma gondii infection was not significantly associated with schizophrenia. Schizophrenia medication, low cat existence in our study area and rare consumption of undercooked meat reasons of our low seropositivity.