Study was undertaken to compare the Echocardiographic changes, with respect to severity of the disease and to observe its association with right ventricular dysfunction, so that the patients can be identified at an earlier stage of the disease. Total of 59 patients confirmed by clinical history, chest radiology, and spirometry were selected and diagnosed as COPD. Patients with history of other lung disease, primary cardiac disease and systemic disease that can cause pulmonary hypertension were excluded. Subjects were further classified according to GOLD(Global Initiative for Chronic obstructive Lung Disease) guidelines and subjected to resting 2D Transthoracic Doppler echocardiography. Echocardiography reviewed to assess the pericardium, valvular anatomy and function, left and right side chamber size, Pulmonary artery systolic pressure and cardiac function. Patients with moderate, severe, and very severe obstruction were 12/59 = 20.3%, 24/59 = 40.6%, and 23/59 = 38.6%, respectively. Pulmonary Hypertension defined as Pulmonary artery systolic pressure (PASP) > 30 mmHg was seen in 21 patients (21/59 = 35.6%). Frequencies of Pulmonary Hypertension in moderate, severe, and very severe obstruction were 1/12 (8.3%), 6/24 (25%), 16/23 (69.5%), respectively. Significant association was seen between FEV1 (Forced Expiratory Volume in one second) P-value=0.035, FVC (Forced Expiratory Volume)P-value=0.001 and Pulmonary artery systolic pressure. We found an association of FEV1 % predicted, FVC% predicted with pulmonary arterial systolic pressure. Furthermore, FEV1 and FVC are associated with an increased risk of pulmonary hypertension. The implications of these findings may be important in the development of new diagnostic algorithms and treatment regimes.